Rucaparib acetate - CAS 773059-23-7

Rucaparib (AG014699) acetate is a highly effective oral inhibitor of PARP proteins, specifically targeting PARP-1, PARP-2, and PARP-3, with a Ki value of 1.4 nM for PARP1. Additionally, it exhibits inhibitory action on hexose-6-phosphate dehydrogenase (H6PD) to a moderate extent. Rucaparib acetate shows promise in the field of research for castration-resistant prostate cancer (CRPC) . [1] [2] [3] [4]

Others, PARP

Others, DNA Damage/DNA Repair, Chromatin/Epigenetic

773029

C21H22FN3O3

383.423

CC(O)=O.CNCc1ccc(cc1)-c1[nH]c2cc(F)cc3C(=O)NCCc1c23

-20°C

Ice Packs

Small Compound