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Rucaparib hydrochloride - CAS 773059-19-1

Rucaparib hydrochloride - CAS 773059-19-1

MF-0037123-01

$1,927.85 USD
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Product Details

  • Bioactivity

    Rucaparib hydrochloride, also known as AG014699, is a powerful and orally active compound that inhibits PARP proteins including PARP-1, PARP-2, and PARP-3 with a Ki value of 1.4 nM for PARP1. Additionally, Rucaparib hydrochloride acts as a modest inhibitor of hexose-6-phosphate dehydrogenase (H6PD) . This compound shows potential in research for castration-resistant prostate cancer (CRPC) [1] [2] [3] [4].

  • Target

    PARP, Others

  • Related Pathways

    Others, Chromatin/Epigenetic, DNA Damage/DNA Repair

  • CAS Number

    773059-19-1

  • Molecular Formula

    C19H19ClFN3O

  • Molecular Weight

    359.83

  • SMILES

    Cl.CNCc1ccc(cc1)-c1[nH]c2cc(F)cc3C(=O)NCCc1c23

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound