Rucaparib tartrate - CAS 773059-22-6

Rucaparib (AG014699) tartrate is an orally active inhibitor of PARP proteins (PARP-1, PARP-2, and PARP-3) and acts on PARP-1 (Ki: 1.4 nM) . It is also a hexose hexaphosphate dehydrogenase (H6PD) inhibitor and has potential for use in the study of destructive resistant prostate cancer (CRPC) .

Others, PARP

Others, Chromatin/Epigenetic, DNA Damage/DNA Repair

773031

C23H24FN3O7

473.457

O[C@H]([C@@H](O)C(O)=O)C(O)=O.CNCc1ccc(cc1)-c1[nH]c2cc(F)cc3C(=O)NCCc1c23

-20°C

Ice Packs

Small Compound