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Rugonersen sodium - CAS 2591588-58-6
Rugonersen sodium - CAS 2591588-58-6
SKU:MF-0121795-01
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Product Details
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Bioactivity
Rugonersen sodium is a locked nucleic acid (LNA) -modified antisense oligonucleotide (ASO) designed to reduce the silencing of ubiquitin protein ligase E3A (UBE3A) . Angelman syndrome (AS) refers to a severe neurodevelopmental disorder caused by the loss of neuronal E3 ligase UBE3A, and Rugonersen has been studied for its potential use in the treatment of AS.
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Target
E1/E2/E3 Enzyme
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Related Pathways
Ubiquitination
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CAS Number
2591588-58-6
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Molecular Formula
C204H235N63Na19O109P19S19
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Molecular Weight
6948
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound