Rusfertide - CAS 1628323-80-7

Rusfertide, a peptide mimetic of natural hepcidin, targets and degrades ferroportin, thereby reducing serum iron and transferrin saturation, which helps regulate red blood cell production. It ameliorates conditions such as polycythemia vera, β-thalassemia, and hereditary hemochromatosis [1] [2].

Ferroportin

Membrane transporter/Ion channel

1628323-80-7

C114H181N27O28S2

2441.95

C([C@@H](NC([C@H](CC1=CN=CN1)NC([C@@H](NC([C@@H](NC(CC(C)C)=O)CC(O)=O)=O)[C@@H](C)O)=O)=O)CC2=CC=CC=C2)(=O)N3[C@H](C(N[C@@H]4C(=O)N[C@@]([C@H](CC)C)(C(=O)N[C@@H](CCCCNC(CC[C@H](NC(CCCCCCCCCCCCCCC)=O)C(O)=O)=O)C(=O)N[C@@H](CC5=CC=CC=C5)C(=O)N[C@@H](CCC(O)=O)C(=O)N6[C@](C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@H](C(N[C@@H](CCCCN)C(N)=O)=O)CSSC4)(CCC6)[H])[H])=O)CCC3

-20°C

Ice Packs

Peptide