Ruxolitinib - CAS 941678-49-5

Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective. Rixolitinib exhibits antitumor activity and induces autophagy and apoptosis.

Apoptosis, Mitophagy, Autophagy, JAK, Tyrosine Kinases

Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, JAK/STAT signaling, Apoptosis, Stem Cells, Autophagy, Angiogenesis

941624

>99.99%

C17H18N6

306.36

N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12

-20°C

Ice Packs

Small Compound