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Ruxolitinib sulfate - CAS 1092939-16-6
Ruxolitinib sulfate - CAS 1092939-16-6
SKU:MF-0138024-01
Regular price
$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
Ruxolitinib sulfate (INCB018424 sulfate) is a potent, selective inhibitor of JAK1/2 with IC50 values of 3.3 nM/2.8 nM, demonstrating over 130-fold selectivity for JAK1/2 compared to JAK3.
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Target
Others, JAK, Autophagy
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Related Pathways
Angiogenesis, Others, Stem Cells, Chromatin/Epigenetic, Tyrosine Kinase/Adaptors, Autophagy, JAK/STAT signaling
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CAS Number
1092917
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Molecular Formula
C17H20N6O4S
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Molecular Weight
404.45
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SMILES
OS(O)(=O)=O.N#CC[C@@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound