RWJ-58643 - CAS 287183-00-0

RWJ-58643 is a β-trypsin and trypsin inhibitor used in studies to inhibit allergic inflammatory conditions. The compound was effective in reducing nasal allergy symptoms, eosinophil infiltration, and interleukin-5 (IL-5) levels at a lower dose (100 mg) . However, at higher doses (300 mg and 600 mg), an increase in eosinophils and elevated IL-5 levels were observed, showing a clear dose-dependent response.

Others, Serine Protease

Others, Proteases/Proteasome

287183-00-0

C20H26N6O4S

446.52

C(C(NC(=O)[C@H]1N(C(C)=O)C[C@H](O)C1)CCCNC(=N)N)(=O)C2=NC=3C(S2)=CC=CC3

-20°C

Ice Packs

Small Compound