RWJ-58643 HCl - CAS 287182-52-9

RWJ 58643 is a reversible beta-tryptase and trypsin inhibitor. Low-dose RWJ-58643 (100 microg) and budesonide (200 microg) significantly reduced symptoms, eosinophils and levels of IL-5 following NAC. However, higher doses of RWJ-58643 (300 and 600 microg) caused a late eosinophilia and preceding increases in IL-5 compared with placebo.

Others, Serine Protease

Proteases/Proteasome, Others

287121

C20H27ClN6O4S

482.984

C(C(NC(=O)[C@H]1N(C(C)=O)C[C@H](O)C1)CCCNC(=N)N)(=O)C2=NC=3C(S2)=CC=CC3.Cl

-20°C

Ice Packs

Small Compound