(RXR) 4XB - CAS 879010-15-8

(RXR) 4XB is a cell-penetrating peptide that binds to phosphorodiamidate morpholino oligomer (PMO), resulting in a peptide-conjugated PMO (PPMO) and enhancing the delivery of PMO into bacterial cells. The (RXR) 4XB-PMO conjugate prevents biofilm formation, inhibits Pseudomonas aeruginosa (with an MIC50 of 0.5-16 μM), and reduces bacterial load in a mouse acute pneumonia model.

Antibacterial

Microbiology/Virology

879010-15-8

C81H158N38O15

1904.37

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-20°C

Ice Packs

Peptide