(S) -4-methyl-N- (3- (4-methyl-1H-imidazol-1-yl) -5- (trifluoromethyl) phenyl) -2- (pyrimidin-5-yl) -1,2,3,4-tetrahydroisoquinoline-7-carboxamide - CAS 1934246-20-4

MitoBloCK-6 is an effective inhibitor of Erv1/ALR with IC50 values of 900 nM and 700 nM, respectively. Additionally, MitoBloCK-6 inhibits Erv2 (IC50=1.4 μM) . It induces apoptosis in hESCs by promoting the release of cytochrome c.

Discoidin Domain Receptor (DDR)

Tyrosine Kinase/Adaptors

1934222

0.9987

C26H23F3N6O

492.5

C[C@H]1C=2C(CN(C1)C=3C=NC=NC3)=CC(C(NC4=CC(=CC(C(F)(F)F)=C4)N5C=NC(C)=C5)=O)=CC2

-20°C

Ice Packs

Small Compound