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Molfinity

(S) -AMG-510 - CAS 2252403-56-6

(S) -AMG-510 - CAS 2252403-56-6

SKU:MF-0017161-01

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  • Bioactivity

    (S) -AMG-510 is the S-type compound of AMG-510 (Sotorasib), which effectively and selectively inhibits KRASG12C through covalent interaction with mutant cysteine, thereby promoting clinical efficacy in KRASG12C tumors.

  • Target

    Kras, Ras, p38 MAPK

  • Related Pathways

    MAPK, GPCR/G Protein

  • CAS Number

    2252341

  • Purity

    0.9976

  • Molecular Formula

    C30H30F2N6O3

  • Molecular Weight

    560.594

  • SMILES

    O=C1N(C=2C(C(=N1)N3[C@@H](C)CN(C(C=C)=O)CC3)=CC(F)=C(N2)C4=C(F)C=CC=C4O)C5=C(C(C)C)N=CC=C5C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound