(S) -CDK2 degrader 6 - CAS 3083777-51-6

(S) -CDK2 degrader 6 (Compound 8) is the S-enantiomer of CDK2 degrader 6. This selective CDK2 molecular glue degrader has a DC50 of 166.7 nM within 24 hours and is applicable in breast cancer research.

Molecular Glues, CDK

PROTAC, Cell Cycle/Checkpoint

3083720

C23H22F5N5O3

511.44

C(F)(F)(F)C12CC(C1)(C2)C=3OC(N[C@@H]4[C@@H](C)N(C4)C5=CC(F)=C(C(F)=C5)[C@H]6C(=O)NC(=O)CC6)=NN3

-20°C

Ice Packs

PROTAC