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(S) -crizotinib - CAS 1374356-45-2
(S) -crizotinib - CAS 1374356-45-2
SKU:MF-0018387-01
Regular price
$32.42 USD
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$32.42 USD
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Product Details
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Bioactivity
(S) -crizotinib (ent-crizotinib) (IC50 of 72 nM), an effective MTH1 (NUDT1) inhibitor, is the (S) -enantiomer of crizotinib.
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Target
MTH1, Apoptosis, DNA/RNA Synthesis
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Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Apoptosis
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CAS Number
1374309
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Purity
0.9989
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Molecular Formula
C21H22Cl2FN5O
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Molecular Weight
450.34
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SMILES
C[C@H](Oc1cc(cnc1N)-c1cnn(c1)C1CCNCC1)c1c(Cl)ccc(F)c1Cl
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound