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Molfinity

(S) -crizotinib - CAS 1374356-45-2

(S) -crizotinib - CAS 1374356-45-2

SKU:MF-0018387-01

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  • Bioactivity

    (S) -crizotinib (ent-crizotinib) (IC50 of 72 nM), an effective MTH1 (NUDT1) inhibitor, is the (S) -enantiomer of crizotinib.

  • Target

    MTH1, Apoptosis, DNA/RNA Synthesis

  • Related Pathways

    DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Apoptosis

  • CAS Number

    1374309

  • Purity

    0.9989

  • Molecular Formula

    C21H22Cl2FN5O

  • Molecular Weight

    450.34

  • SMILES

    C[C@H](Oc1cc(cnc1N)-c1cnn(c1)C1CCNCC1)c1c(Cl)ccc(F)c1Cl

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound