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(S) -Deoxy-thalidomide - CAS 107657-57-8
(S) -Deoxy-thalidomide - CAS 107657-57-8
SKU:MF-0035111-01
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Product Details
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Bioactivity
(S) -Deoxy-thalidomide functions as a ligand for E3 ubiquitin ligases. It is linked to target protein ligands via a linker, forming PROTACK-Ras Degrader-3. This compound specifically targets and degrades mutant KRAS proteins.
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Target
Kras, Ras, Ligand for E3 Ligase
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Related Pathways
MAPK, PROTAC
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CAS Number
107592
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Molecular Formula
C13H12N2O3
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Molecular Weight
244.25
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SMILES
O=C1N(CC=2C1=CC=CC2)[C@@H]3C(=O)NC(=O)CC3
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
PROTAC