S-Gem - CAS 2169925-98-6

S-Gem, a thioredoxin reductase (TrxR) -dependent prodrug of Gemcitabine, is selectively activated by TrxR. Studies indicate that S-Gem exhibits lower cytotoxicity than Gemcitabine [1].

Autophagy, Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis

Cell Cycle/Checkpoint, Apoptosis, DNA Damage/DNA Repair, Autophagy

2169821

C13H15F2N3O6S2

411.4

FC1(F)[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)N=C(NC(OC3CSSC3)=O)C=C2

-20°C

Ice Packs

Small Compound