(S) -Indoximod - CAS 21339-55-9

(S) -Indoximod (L-Abrine) exhibits inhibition of rabbit small intestine indoleamine 2, 3-dioxygenase, competitive inhibition of IDO, reduction of Foxp3 protein expression in tumor of C57BL/6 mouse allografted with mouse LLC cells at 200 mg/kg, induction of IDO1 protein expression in tumor of C57BL/6 mouse allografted with mouse LLC cells at 200 mg/kg, antitumor activity against mouse LLC cells allografted in C57BL/6 mouse, antiproliferative activity against mouse LLC cells at 50 uM.

IDO, Indoleamine 2,3-Dioxygenase (IDO)

Metabolism

21275

0.9969

C12H14N2O2

218.25

Cn1cc(C[C@H](N)C(O)=O)c2ccccc12

-20°C

Ice Packs

Natural Product