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Molfinity

(S) -JDQ-443 - CAS 2653994-10-4

(S) -JDQ-443 - CAS 2653994-10-4

SKU:MF-0035155-01

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  • Bioactivity

    (S) -JDQ-443 is an isomer of JDQ-443, which is an orally active, potent, selective, and covalent KRAS G12C inhibitor, showing antitumor activity [1] [2].

  • Target

    Ras, Others, Kras, PERK

  • Related Pathways

    MAPK, Others, Apoptosis, GPCR/G Protein

  • CAS Number

    2653980

  • Molecular Formula

    C29H28ClN7O

  • Molecular Weight

    526.03

  • SMILES

    CC1=C(C(=NN1C2CC3(C2)CN(C(C=C)=O)C3)C=4C=C5C(=CC4)N(C)N=C5)C6=C7C(=CC(C)=C6Cl)NN=C7

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound