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S-methyl DM1 - CAS 912569-84-7
S-methyl DM1 - CAS 912569-84-7
SKU:MF-0027489-01
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$1,515.42 USD
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$1,515.42 USD
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Product Details
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Bioactivity
S-methyl DM1, a thiomethyl derivative of Maytansine, binds to tubulin (Kd of 0.93 μM) and inhibits microtubule polymerization.
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Target
ADC Cytotoxin, Microtubule Associated
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Related Pathways
Antibody-drug Conjugate/ADC Related, Cytoskeletal Signaling
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CAS Number
912478
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Molecular Formula
C36H50ClN3O10S
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Molecular Weight
752.31
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SMILES
C[C@]12[C@@](O1)([C@H](C)[C@@]3(C[C@](O)([C@H](OC)/C=C/C=C(\C)/CC4=CC(N(C)C(=O)C[C@@H]2OC([C@@H](N(C(CCSC)=O)C)C)=O)=C(Cl)C(OC)=C4)NC(=O)O3)[H])[H]
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound