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Molfinity

S-methyl DM1 - CAS 912569-84-7

S-methyl DM1 - CAS 912569-84-7

SKU:MF-0027489-01

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  • Bioactivity

    S-methyl DM1, a thiomethyl derivative of Maytansine, binds to tubulin (Kd of 0.93 μM) and inhibits microtubule polymerization.

  • Target

    ADC Cytotoxin, Microtubule Associated

  • Related Pathways

    Antibody-drug Conjugate/ADC Related, Cytoskeletal Signaling

  • CAS Number

    912478

  • Molecular Formula

    C36H50ClN3O10S

  • Molecular Weight

    752.31

  • SMILES

    C[C@]12[C@@](O1)([C@H](C)[C@@]3(C[C@](O)([C@H](OC)/C=C/C=C(\C)/CC4=CC(N(C)C(=O)C[C@@H]2OC([C@@H](N(C(CCSC)=O)C)C)=O)=C(Cl)C(OC)=C4)NC(=O)O3)[H])[H]

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound