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S-N6-Methyladenosylhomocysteine - CAS 53228-06-1

S-N6-Methyladenosylhomocysteine - CAS 53228-06-1

MF-0112755-01

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Product Details

  • Bioactivity

    S-N6-Methyladenosylhomocysteine (Chart 1-1) is a potent inhibitor of the histone methyltransferase DOT1L, with an IC50 of 0.29 μM. This compound plays a significant role in cancer research.

  • Target

    Histone Methyltransferase

  • Related Pathways

    Chromatin/Epigenetic

  • CAS Number

    53228-06-1

  • Molecular Formula

    C15H22N6O5S

  • Molecular Weight

    398.437

  • SMILES

    O[C@H]1[C@H](N2C=3C(N=C2)=C(NC)N=CN3)O[C@H](CSCC[C@@H](C(O)=O)N)[C@H]1O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound