(S) -p38 MAPK Inhibitor III - CAS 581098-48-8

(S) -p38 MAPK inhibitor III is a methylsulfanylimidazole that inhibits p38 MAP kinase (IC50 = 0.90 μM in vitro) . It is cell-permeable, potently blocking the release of TNF-α and IL-1β from human peripheral blood mononuclear cells (IC50s = 0.37 and 0.044 μM, respectively) .

Others, p38 MAPK

MAPK, Others

581042

C23H21FN4S

404.5

S(C)C=1NC(=C(N1)C=2C=C(N[C@@H](C)C3=CC=CC=C3)N=CC2)C4=CC=C(F)C=C4

-20°C

Ice Packs

Small Compound