(S) -Padsevonil - CAS 1294001-37-8

(S) -Padsevonil is the S-enantiomer of Padsevonil. Padsevonil (UCB0942) is a potent antiepileptic agent that selectively targets both presynaptic and postsynaptic sites. It binds with high affinity to synaptic vesicle protein 2 (SV2) and acts as a positive allosteric modulator and partial agonist of GABAAR, showing greater efficacy on receptors containing α1 and α5 subunits. Padsevonil demonstrates antiepileptic effects in various rodent models.

GABA Receptor

Membrane transporter/Ion channel, Neuroscience

1294001-37-8

C14H14ClF5N4O2S

432.8

C(C=1N2C(=NC1C(F)(F)F)SC(COC)=N2)N3C[C@H](CC(Cl)(F)F)CC3=O

-20°C

Ice Packs

Inhibitors & Agonists