(S) -PI3K-IN-2 - CAS 1403458-27-4

(S) -PI3K-IN-2 is the enantiomer of PI3K-IN-2, functioning as a ΡΙ3Κβ/δ inhibitor with IC50 values of 0.198 and 0.282 μM, respectively. It can also inhibit the phosphorylation of AKT (ser473) in MDA-MB-468 cells, with an IC50 of 27 nM.

PI3K

PI3K/Akt/mTOR signaling

1403427

C28H29F2N3O5

525.544

C(=O)(C1=CC(=C2C(=C1)C(=O)C=C(O2)N3CCOCC3)[C@H]4N(CCC4)C5=CC(F)=CC(F)=C5)N6CCOCC6

-20°C

Ice Packs

Small Compound