(S) -PI3Kα-IN-4 - CAS 2322293-84-3

(S) -PI3Kα-IN-4, a potent inhibitor of PI3Kα with an IC50 of 2.3 nM, demonstrates 38.3-, 4.25-, and 4.93-fold selectivity over PI3Kβ, PI3Kδ, and PI3Kγ, respectively, and is suitable for cancer research[1]. (S) -PI3Kα-IN-4 (compound 11) is a quinazolin-4 (3H) -one derivative with 2-substituted-N-methylpropanamide substitution[1].

Others, PI3K

PI3K/Akt/mTOR signaling, Others

2322206

C25H23ClFN5O5S

560

CNC(=O)[C@@H](C)Cn1cnc2ccc(cc2c1=O)-c1cnc(OC)c(NS(=O)(=O)c2ccc(F)cc2Cl)c1

-20°C

Ice Packs

Small Compound