(S, R, S) -AHPC-C5-COOH - CAS 2267282-19-7

(S, R, S) -AHPC-C5-COOH (VH032-C5-COOH) is a synthesized conjugate for E3 ligase ligand-linker applications, combining the VH032 VHL-based ligand with a linker for PROTAC development. VH-032 is a selective and potent VHL/HIF-1α interaction inhibitor with a dissociation constant (Kd) of 185 nM, offering potential in anemia and ischemic diseases research[1].

Others, HIF/HIF Prolyl-Hydroxylase, E3 Ligase Ligand-Linker Conjugate

Metabolism, PROTAC, Chromatin/Epigenetic, Others

2267256

C29H42N4O5S

558.73

Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NCCCCCCC(O)=O)C(C)(C)C)cc1

-20°C

Ice Packs

PROTAC