(S, R, S) -AHPC-O-PEG1-propargyl - CAS 2098799-79-0

(S, R, S) -AHPC-O-PEG1-propargyl, serves as an E3 ligand essential for PROTAC [1] synthesis. Additionally, this compound functions as a click chemistry reagent equipped with an Alkyne group, facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAc) with Azide-containing molecules.

E3 Ligase Ligand-Linker Conjugate

PROTAC

2098799-79-0

C29H38N4O6S

570.7

C([C@@H](NC(COCCOCC#C)=O)[C@@](C)(C)C)(=O)N1[C@H](C(NCC2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@@H](O)C1

-20°C

Ice Packs

PROTAC