(S, R, S) -AHPC-O-Ph-PEG1-NH2 - CAS 2361117-24-8

(S, R, S) -AHPC-O-Ph-PEG1-NH2 (VH032-O-Ph-PEG1-NH2) is an E3 ligase ligand-linker conjugate that combines a VHL ligand for the E3 ubiquitin ligase with a PROTAC linker; it is used in PROTAC EED degrader-1, targeting EED with a potency (pKD) of 9.02[1].

E3 Ligase Ligand-Linker Conjugate, Others

Others, PROTAC

2361085

C32H41N5O6S

623.76

Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COc2ccc(OCCN)cc2)C(C)(C)C)cc1

-20°C

Ice Packs

PROTAC