(S, R, S) -AHPC-PEG4-NHS ester - CAS 2757045-59-1

(S, R, S) -AHPC-PEG4-NHS ester is a PROTAC linker that fuses an E3 ligase ligand with a PEG4 spacer, enhancing PROTAC drug chemistry. It reacts with amine molecules, and the inclusion of the PEG4 arm improves the solubility of the molecule.

PROTAC Linker

PROTAC

2756985

C38H53N5O12S

803.919

C(C(NC(CCOCCOCCOCCOCCC(ON1C(=O)CCC1=O)=O)=O)C(C)(C)C)(=O)N2[C@H](C(NCC3=CC=C(C=C3)C4=C(C)N=CS4)=O)C[C@@H](O)C2

-20°C

Ice Packs

PROTAC