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(S, R, S) -AHPC-PEG6-Tos - CAS 2839806-94-7
(S, R, S) -AHPC-PEG6-Tos - CAS 2839806-94-7
SKU:MF-0035366-01
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Product Details
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Bioactivity
(S, R, S) -AHPC-PEG6-Tos is a compound combining a VHL recruiter ligand and a polyethylene glycolated crosslinker with a tosyl group. The tosyl group serves as a good leaving group in nucleophilic substitution reactions. (S, R, S) -AHPC-PEG2-Tos is applicable in the synthesis of PROTAC compounds and for molecules designed for targeted protein degradation.
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Target
E3 Ligase Ligand-Linker Conjugate
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Related Pathways
PROTAC
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CAS Number
2839705
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Molecular Formula
C42H60N4O12S2
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Molecular Weight
877.075
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SMILES
C([C@@H](NC(CCOCCOCCOCCOCCOCCOS(=O)(=O)C1=CC=C(C)C=C1)=O)[C@](C)(C)C)(=O)N2[C@H](C(NCC3=CC=C(C=C3)C4=C(C)N=CS4)=O)C[C@@H](O)C2
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
PROTAC