(S, R.S) -AHPC-PEG8-acid - CAS 2428400-60-4

(S, R, S) -AHPC-PEG8-acid is a synthetic PROTAC linker that binds an E3 ligase ligand with a PEG8 linker to facilitate PROTAC drug development. The PEG8 component enhances the compound's water solubility, and the acid group reacts with amine-containing molecules.

PROTAC Linker

PROTAC

2428336

C42H66N4O14S

883.057

C([C@@H](NC(COCCOCCOCCOCCOCCOCCOCCOCCCC(O)=O)=O)[C@](C)(C)C)(=O)N1[C@H](C(NCC2=CC=C(C=C2)C=3SC=NC3C)=O)C[C@@H](O)C1

-20°C

Ice Packs

PROTAC