(S, S) -PLX-4545 - CAS 2892065-49-3

(S, S) -PLX-4545 (Compound I) is an orally active cereblon-based molecular glue degrader targeting IKZF2 (zinc finger transcription factor Helios) . It is useful for studying diseases or conditions mediated by IKZF2, such as proliferative disorders and/or cancer.

Molecular Glues, IKZF

Immunology/Inflammation, PROTAC

2892013

C28H31N3O4

473.56

O([C@@H]1[C@H](CCCC1)N2CC(C2)C3=CC=CC=C3)C=4C=C5C(=CC4)C(=O)N(C5)C6C(=O)NC(=O)CC6

-20°C

Ice Packs

PROTAC