(S, S) -Z-FA-FMK - CAS 105637-38-5

(S, S) -Z-FA-FMK is a cell-permeable, irreversible inhibitor of cathepsin B. This compound inhibits the production of IL-1α and IL-1β induced by LPS. Additionally, (S, S) -Z-FA-FMK serves as a negative control for caspase-1 and caspase-2 inhibitors due to the absence of an aspartic acid residue at the P1 position.

Cysteine Protease

Proteases/Proteasome

105637-38-5

C21H23FN2O4

386.42

[C@H](CC1=CC=CC=C1)(C(N[C@H](C(CF)=O)C)=O)NC(OCC2=CC=CC=C2)=O

-20°C

Ice Packs

Peptide