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S1R agonist 1 - CAS 193354-70-0

S1R agonist 1 - CAS 193354-70-0

SKU:MF-0154985

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  • Bioactivity

    Compound 6b, also known as S1R agonist 1, is a selective agonist for S1R with dissociation constants (Ki) of 0.93 nM for S1R and 72 nM for S2R. This compound demonstrates neuroprotective effects against reactive oxygen species (ROS) and NMDA-induced neurotoxicity [1].

  • Target

    Others, Sigma receptor

  • Related Pathways

    GPCR/G Protein, Others

  • CAS Number

    193284

  • Molecular Formula

    C20H25NO

  • Molecular Weight

    295.42

  • SMILES

    C(C1CCN(CCOC2=CC=CC=C2)CC1)C3=CC=CC=C3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound