S65487 hydrochloride - CAS 1644543-95-2

S65487 (VOB560) hydrochloride, a potent and selective Bcl-2 inhibitor, is effective against BCL-2 mutations, including G101V and D103Y, while exhibiting poor affinity for MCL-1, BFL-1, and BCL-XL. This compound induces apoptosis and possesses anticancer activities.

Others, Apoptosis, Bcl-2 Family

Apoptosis, Others

1644446

C41H42Cl2N6O4

753.73

Cl.Cc1c(cc(C#N)n1C)N(C(=O)c1cc(-c2cc(Cl)ccc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n(C)c1C)c1ccc(O)cc1

-20°C

Ice Packs

Small Compound