SA09-Cu - CAS 155641-16-0

SA09-Cu is a potent, noncompetitive inhibitor of NDM-1, with an IC50 of 9.6 nM. It inactivates NDM-1 by oxidizing the enzyme's Zn (II) -thiolate site and resists reduction by bacterial intracellular thiols. SA09-Cu effectively restores Meropenem efficacy against various clinical NDM-1-producing carbapenem-resistant Enterobacteriaceae (CRE) and hampers the progression of carbapenem resistance [1].

Others, Antibacterial

Others, Microbiology/Virology

155625

C8H16CuN2O2S4

364.03

N(CCO)(C)C=1[S-][Cu+2]2([S-]C(N(CCO)C)=[S]2)[S]1

-20°C

Ice Packs

Small Compound