Sacituzumab tirumotecan - CAS 2768350-77-0

Sacituzumab tirumotecan (SKB264) is an antibody-drug conjugate (ADC) targeting TROP2 (trophoblast cell surface antigen 2), capable of releasing the active payload KL610023 within TROP2-positive tumour cells. an effective topoisomerase I inhibitor that induces DNA damage and leads to cell cycle arrest and apoptosis, for use in non-small cell lung cancer (NSCLC) and triple-negative breast cancer (TNBC) .

Antibody-Drug Conjugates (ADCs), TROP2

Immunology/Inflammation, Antibody-drug Conjugate/ADC Related

2768350-77-0

0.99

-20°C

Ice Packs

Inhibitory Antibodies