Safinamide - CAS 133865-89-1

Safinamide (FCE-26743) is a reversible and selective monoamine oxidase B (IC50 0.098μM) inhibitor, reducing the degradation of dopamine, and a glutamate release inhibitor (IC50 8μM) . It also inhibits dopamine reuptake. Safinamide also blocks sodium and calcium channels. Potential additional uses of Safinamide might be Parkinson's disease, restless leg syndrome and epilepsy.

MAO, Monoamine Oxidase, Sodium Channel

Neuroscience, Metabolism, Membrane transporter/Ion channel

133775

0.9992

C17H19FN2O2

302.34

O(CC1=CC(F)=CC=C1)C2=CC=C(CN[C@H](C(N)=O)C)C=C2

-20°C

Ice Packs

Small Compound