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Molfinity

SAFit2 - CAS 1643125-33-0

SAFit2 - CAS 1643125-33-0

SKU:MF-0016382-01

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  • Bioactivity

    SAFit2 is a highly potent and selective inhibitor of fk506 binding protein 51 (FKBP51) with a Ki value of 6 nM. SAFit2 can enhance the binding of AKT2-AS160 and participate in the downstream response of glucocorticoid release in vivo. It is a candidate compound for the treatment of obesity, chronic pain, depression and anxiety.

  • Target

    FKBP

  • Related Pathways

    Autophagy, Immunology/Inflammation, Apoptosis

  • CAS Number

    1643092

  • Purity

    >99.99%

  • Molecular Formula

    C46H62N2O10

  • Molecular Weight

    802.99

  • SMILES

    COc1ccc(CC[C@@H](OC(=O)[C@@H]2CCCCN2C(=O)[C@@H](C2CCCCC2)c2cc(OC)c(OC)c(OC)c2)c2cccc(OCCN3CCOCC3)c2)cc1OC

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound