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Molfinity

SAG - CAS 912545-86-9

SAG - CAS 912545-86-9

SKU:MF-0034803-01

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  • Bioactivity

    SAG (Smoothened Agonist) is a Smo receptor agonist (EC50=3 nM) that is cell-permeable and selective. SAG regulates Smo activity by binding directly to the Smo helix and can activate the Hedgehog signaling pathway.

  • Target

    Hedgehog/Smoothened, Smo

  • Related Pathways

    Stem Cells, GPCR/G Protein

  • CAS Number

    912450

  • Purity

    0.9888

  • Molecular Formula

    C28H28ClN3OS

  • Molecular Weight

    490.06

  • SMILES

    CN[C@H]1CC[C@@H](CC1)N(Cc1cccc(c1)-c1ccncc1)C(=O)c1sc2ccccc2c1Cl

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound