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SAG dihydrochloride - CAS 2702366-44-5
SAG dihydrochloride - CAS 2702366-44-5
SKU:MF-0014254-01
Regular price
$45.88 USD
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$45.88 USD
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Product Details
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Bioactivity
SAG dihydrochloride, a powerful agonist of the Smoothened (Smo) receptor (EC 50 = 3 nM; Kd = 59 nM), effectively activates the Hedgehog signaling pathway. It also negates the effects of Cyclopamine inhibition on Smo.
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Target
Smo, Hedgehog/Smoothened
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Related Pathways
Stem Cells, GPCR/G Protein
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CAS Number
2702317
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Purity
>99.99%
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Molecular Formula
C28H30Cl3N3OS
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Molecular Weight
562.98
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SMILES
O=C(C1=C(C2=CC=CC=C2S1)Cl)N([C@@H]3CC[C@H](CC3)NC)CC4=CC(C5=CC=NC=C5)=CC=C4.Cl.Cl
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound