Molfinity
Saikosaponin A - CAS 20736-09-8
Saikosaponin A - CAS 20736-09-8
SKU:MF-0017951-01
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Product Details
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Bioactivity
Saikosaponin A has a variety of pharmacological benefits, including antiepileptic, anti-osteoporosis, antioxidant, anti-in ammatory, immunomodulatory, and anti-bacterial activities. It can effectively attenuate neuropathic pain in CCI rats by inhibiting the activation of p38 MAPK and NF-κB signaling pathways in spinal cord. It can inhibit NMDA receptor current and persistent sodium current, and inhibit the TNF-α level, the IL-1β production, and cysteine-aspartic acid protease (caspase) -1 activity.
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Target
Antibacterial, Liver X Receptor, NF-κB
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Related Pathways
Microbiology/Virology, NF-κB, Metabolism
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CAS Number
20736-09-8
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Purity
0.9988
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Molecular Formula
C42H68O13
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Molecular Weight
780.98
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SMILES
[H][C@@]12CC(C)(C)CC[C@@]11CO[C@@]22C=C[C@]3([H])[C@@]4(C)CC[C@H](O[C@]5([H])O[C@H](C)[C@H](O)[C@H](O[C@]6([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@H]5O)[C@@](C)(CO)[C@]4([H])CC[C@@]3(C)[C@]2(C)C[C@@H]1O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Natural Product