SAJM589 - CAS 2089-82-9

SAJM589 is a Myc inhibitor that dose-dependently disrupts Myc-Max heterodimers, thereby decreasing Myc protein levels. Myc is a multifunctional nuclear phosphoprotein that plays a key role in cell cycle progression, apoptosis, and cellular transformation. sAJM589 inhibits the cellular proliferation of a variety of Myc-dependent cancer cell lines and the adherent, non-dependent growth of Raji cells’ Growth.

C-Myc

Cell Cycle/Checkpoint

1998

C16H10N2O

246.26

OC=1C=C2N=C3C=CC=CC3=NC2=C4C=CC=CC14

-20°C

Ice Packs

Small Compound