Salidroside - CAS 10338-51-9

Salidroside is a bioactive phenolic glycoside compound isolated from Rhodiola rosea and is a prolyl endopeptidase inhibitor. Salidroside can alleviate cachexia symptoms in a tumor cachexia mouse model by activating mTOR signaling and protect dopaminergic neurons by enhancing PINK1/Parkin-mediated mitochondrial autophagy. Salidroside can also inhibit the growth of cancer cells by regulating the CDK4-cyclin D1 pathway to block the G1 phase and/or regulating the Cdc2-cyclin B1 pathway to block the G2 phase.

Apoptosis, mTOR, PTEN, Prolyl Endopeptidase (PREP)

Metabolism, PI3K/Akt/mTOR signaling, Apoptosis, Proteases/Proteasome

10278

0.9925

C14H20O7

300.3

OCC1OC(OCCc2ccc(O)cc2)C(O)C(O)C1O

-20°C

Ice Packs

Natural Product