Salvinorin A Carbamate - CAS 858345-57-0

Salvinorin A carbamate, a potent κ-opioid receptor (KOR) full agonist, exhibits nearly the same potency as salvinorin A, with EC50 values of 6.2 and 4.5 nM, respectively, for activating the human KOR to augment the binding of [35S]GTPγS. Enhancing biological stability, the addition of a carbamate group to salvinorin A reduces deacetylation.

Others, Opioid Receptor

Endocrinology/Hormones, GPCR/G Protein, Others, Neuroscience

858345-57-0

C22H27NO8

433.457

COC(=O)[C@@H]1C[C@H](OC(N)=O)C(=O)[C@H]2[C@@]1(C)CC[C@H]1C(=O)O[C@@H](C[C@]21C)c1ccoc1

-20°C

Ice Packs

Small Compound