Sanglifehrin A - CAS 187148-13-6

Sanglifehrin A is an immunosuppressive macrocyclic natural product. It enhances the complex formation between cyclophilin A and inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) .

Molecular Glues

PROTAC

187148-13-6

C60H91N5O13

1090.39

C[C@@H]1[C@]2(O[C@@H](C[C@@H]([C@H](CC/C=C/C=C(\C)/[C@H]3OC(=O)[C@]4(NN(C(=O)[C@H](CC5=CC(O)=CC=C5)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCC(C)=O)[C@H](O)[C@@H](C)[C@@H](O)\C=C\C=C\C3)CCC4)[H])C)O)[C@H](C)[C@H](O)[C@@H]2C)NC(=O)[C@@H](CC)C1

-20°C

Ice Packs

Natural Product