(Sar1, Ile4,8) -Angiotensin II - CAS 185461-45-4

(Sar1, Ile4,8) -Angiotensin II is a functionally selective agonist for the angiotensin II type 1 receptor (AT1R), enhancing insulin-stimulated signaling of the insulin receptor (IR) and glycogen synthesis, and boosting the insulin-induced phosphorylation of Akt and GSK3α/β [1].

RAAS

Endocrinology/Hormones

185412

C43H75N13O9

918.14

CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC)C(C)C)[C@@H](C)CC)[C@@H](C)CC)C(O)=O

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