Molfinity

SAR502250 - CAS 503860-57-9

SKU:MF-0138904-01

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Product Details

Bioactivity
SAR502250 is a potent, selective, ATP-competitive, orally active, and brain-penetrant GSK3 inhibitor with a human GSK-3β IC50 value of 12 nM, exhibiting antidepressant-like activity and being researched for potential application in Alzheimer's disease (AD) treatment.
Target
GSK-3, Others
Related Pathways
Others, PI3K/Akt/mTOR signaling, Stem Cells
CAS Number
503794
Molecular Formula
C19H18FN5O2
Molecular Weight
367.38
SMILES
Cn1c(nc(cc1=O)-c1ccncn1)N1CCO[C@H](C1)c1ccc(F)cc1
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound