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SARM1-IN-6 - CAS 3080315-51-8
SARM1-IN-6 - CAS 3080315-51-8
SKU:MF-0118133-01
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Product Details
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Bioactivity
SARM1-IN-6 (Compound 17a) is a brain-penetrant orthosteric inhibitor of SARM1. It exhibits an IC50 of 14 nM against NAM and 74 nM against HEK cells.
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Target
TLR
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Related Pathways
Immunology/Inflammation
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CAS Number
3080256
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Molecular Formula
C20H19F2N3O
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Molecular Weight
355.38
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SMILES
O=C1N(C23CC(C2)(C3)C=4C=CN=CC4)CC[C@@H](C1)C=5C=C(F)C(F)=NC5
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound