SARS-CoV-2-IN-113 - CAS 455304-63-9

SARS-CoV-2-IN-113 (Compound 24) is a sulfonyl hydrazine derivative that exhibits antiviral activity against SARS-CoV-2 infection, with an IC50 of 8.320 μM. It effectively inhibits the entry and replication of SARS-CoV-2 by downregulating genes and proteins such as Spike, ACE-2, and RdRp. SARS-CoV-2-IN-113 shows high selectivity and low cytotoxicity, making it a valuable candidate for COVID-19 research.

Angiotensin-converting Enzyme (ACE), SARS-CoV

Metabolism, Microbiology/Virology

455232

C14H14N2O5S

322.34

O=S(=O)(NN=CC1=CC=C(O)C(O)=C1O)C2=CC=C(C=C2)C

-20°C

Ice Packs

Small Compound