SARS-CoV-2-IN-14 - CAS 22203-98-1

SARS-CoV-2-IN-14 is a potent and oral inhibitor of SARS-CoV-2 (IC50:0.39 μM), which is an analogue of niclosamide. SARS-CoV-2-IN-14 was more stable than niclosamide in the determination of human plasma and liver S9 enzyme. Oral administration of SARS-CoV-2-IN-14 can improve its bioavailability and half-life.

SARS-CoV

Microbiology/Virology

22104

0.9978

C13H9Cl2NO2

282.12

C(NC1=CC(Cl)=CC=C1)(=O)C2=C(O)C=CC(Cl)=C2

-20°C

Ice Packs

Small Compound